Systematic literature review of the complications of primary and secondary tracheoesophageal punctures in patients with laryngectomies for voice restoration


Tracheoesophageal puncture
Laryngeal cancer




Netter Images. Pharynx median section. Available at: (accessed 12.6.18).

Martini FHNJ. Fundamentals of Anatomy and Physiology. 7th ed. San Francisco: Pearson/Benjamin Cummings, 2009.

About Cancer. Head and neck cancer images and anatomy. Available at: (accessed 12.6.18)

Wiegand S. Evidence and evidence gaps of laryngeal cancer surgery. GMS Curr Top in Otorhinolaryngol Head Neck Surg. 2016;15:Doc03. Available from:

EUCAN. Laryngeal Cancer. 2012. Available from: (accessed 12.6.18)

Cattaruzza MS, Maisonnueve P, Boyle P. Epidemiology of laryngeal cancer. Eur J Cancer B Oral Oncol. 1996;32B(5):293-305. Available from:

NICE. Treatment of upper aerodigestive tract cancer. 2016 updated 2018. Available at: (accessed 12.6.18)

Rafferty MA, Fenton JE, Jones AS. The history, aetiology and epidemiology of laryngeal carcinoma. Clinical Otolaryngology & Allied Sciences. 2001;26(6):442-6. Available from:

Ceachir O, Hainarosie R, Zainea V. Total laryngectomy - past, present, future. Maedica. 2014;9(2):210-6. Epub 2015/02/24.

Breaks A. Critical review: effect of primary versus secondary tracheoesophageal puncture (TEP) on voice rehabilitation in patients who have undergone total laryngectomy. 2012. Available at: (accessed 12.6.18).

Deschler DG, Bunting GW, Lin DT, Emerick K, Rocco J. Evaluation of voice prosthesis placement at the time of primary tracheoesophageal puncture with total laryngectomy. Laryngoscope. 2009;119(7):1353-7. Available from:

Roxburgh J, Perry A. Use of a “hands-free” tracheostoma valve in patients with laryngectomy and tracheoesophageal puncture. Annals of Otol, Rhinol, and Laryngol. 2004;113(7):565-70. Available from:

Deschler DG, Emerick KS, Lin DT, Bunting GW. Simplified technique of tracheoesophageal prosthesis placement at the time of secondary tracheoesophageal puncture (TEP). Laryngoscope. 2011;121(9):1855-9. Available from:

Lewin JS, Portwood MA, Wang Y, Hutcheson KA. Clinical application of the Provox NiD voice prosthesis: a longitudinal study. Laryngoscope. 2014;124(7):1585-91. Available from:

Lewin JS. Hutcheson KA. General principles of rehabilitation of speech, voice, and swallowing function after treatment of head and neck cancer. In: Harrison LB et al. Head and Neck Cancer: a Multidisciplinary Approach. Philadelphia: Lippincott, Williams and Wilkins. 2009:168-77.

Singer MI, Blom ED. An endoscopic technique for restoration of voice after laryngectomy. Ann Otol Rhinol Laryngol. 1980;89(6 Pt 1):529-33. Available from:

Cheng E, Ho M, Ganz C, et al. Outcomes of primary and secondary tracheoesophageal puncture: a 16-year retrospective analysis. Ear Nose Throat J. 2006; 85(4):262, 4-7.

Maves MD, Lingeman RE. Primary vocal rehabilitation using the Blom-Singer and Panje voice prostheses. Ann Otol Rhinol Laryngol. 1982; 91(4 Pt 1): 458-60. Available from:

Norsuhazenah PSD, Baki MM, Yunus MRM, Athar PPSH, Abdullah S. Complications following tracheoesophageal puncture: a tertiary hospital experience. Ann Acad Med Singap. 2010;3 (7):565-4.Epub 2010/08/11.

Makitie AA, Niemensivu R, Juvas A, et al. Post laryngectomy voice restoration using a voice prosthesis: a single institution’s ten-year experience. Ann Otol Rhinol Laryngol. 2003;11(12):100710.. Available from:

Boscolo-Rizzo P, Zanetti F, Carpené S, Da Mosto MC. Long-term results with tracheoesophageal voice prosthesis: primary versus secondary TEP. Eur Arch Otorhinolaryngol. 2008;265(1):73-7. Available from:

Imre A, Pinar E, Calli C, et al. Complications of tracheoesophageal puncture and speech valves: retrospective analysis of 47 patients. Kulak Burun Bogaz Ihtis Derg. 2013;23(1):15-20. Available from:

Calder N, MacAndie C, MacGregor F. Tracheoesophageal voice prostheses complications in north Glasgow. J Laryngol Otol. 2006;120(6):487-91. Available from:

Emerick KS, Tomycz L, Bradford CR, et al. Primary versus secondary tracheoesophageal puncture in salvage total laryngectomy following chemoradiation. Otolaryngol Head Neck Surg. 2009;140(3):386-90. Available from:

Van Den Hoogen FJA, Oudes MJ, Hombergen G,Nijdam HF, Manni JJ. The Groningen, Nijdam and Provox voice prostheses: a prospective clinical comparison based on 845 replacements. Acta Otolaryngol. 1996;116(1):119-24. Available from:

Prichard AJ, Powell A, Samuel PR, Stafford FW. Surgical voice restoration: the Sunderland experience. J R Coll Surg Edinb. 1994;39(6):355-9.

Silver FM, Gluckman JL, Donegan JO. Operative complications of tracheoesophageal puncture. Laryngoscope. 1985;95(11):1360-2. Available from: